实验室成员

中国科学院水生生物研究所藻类细胞生物学实验室

电话:027-68780902

地址:湖北省武汉市武昌区东湖南路7号中科院水生所2号楼816

  1. 主页>实验室成员>龙欢

    龙欢



    龙欢,副研究员

    个人简历

      博士,副研究员,硕士生导师。2005年毕业于华中农业大学生命科学技术学院生物技术系,获理学学士学位,同年获武汉大学法学院法学学士学位;2011年毕业于华中农业大学生物化学与分子生物学专业,获理学博士学位。2009年9月至2010年9月曾作为国家公派联合培养博士生在德国弗莱堡大学医学院细胞生物学与解剖学研究所学习一年。2011年以来在中国科学院水生生物研究所工作,2019年7月至2020年7月赴美国加州大学伯克利分校交流访问1年。主要以衣藻和细胞系为模式,研究纤毛蛋白的运输及调控、纤毛的分泌功能及微藻对重金属的感受和转化机理。在Current Biology等杂志上发表SCI收录论文10余篇。作为课题负责人承担有国家自然科学基金项目、国家863计划项目专题、中科院水生所青年人才知识创新功能领域前沿项目等。

    研究方向

    纤毛蛋白的运输及调控
    纤毛囊泡分泌的分子机理和调控机制
    微藻对重金属的感受和转化机理

    招生专业:遗传学

    联系方式邮箱:huanlong#ihb.ac.cn(发邮件时将#换成@);电话:027-68780902

    代表文章:

    1. Long, H and Huang, K. Transport of ciliary membrane proteins. Frontiers in Cell and Developmental Biology, doi: 10.3389/fcell. 00381. 2020

    2. Wang, Q., Peng, Z., Long, H., Deng, X., Huang, K. Polyubiquitylation of α-tubulin at K304 is required for flagellar disassembly in Chlamydomonas. Journal of Cell Science, 132(6). pii: jcs229047. 2019

    3. Long, H., Zhang, F., Xu, N., Liu, G., Diener, D., Rosenbaum, J., Huang, K., Comparative analysis of ciliary membranes and ectosomes. Current Biology, 26: 3327-3335. 2016.

    4. Long, H., Huang, K. Analysis of flagellar protein ubiquitination. Methods in Enzymology, 524: 59-73. 2013.

    5. Long, H., Wang, Q., Huang, K. Ciliary/Flagellar Protein Ubiquitination. Cells, 4: 474-482. 2015.

    6. Long, H., Bock, H H., Lei, T., et al. Identification of alternatively spliced Dab1 and Fyn isoforms in pig. BMC Neuroscience, 12(1): 17. 2011.

    7. Long, H., Zhao, S., Lei, T., Han, J., Yuan, J., Qi, Y., Yang, Z. Cloning and spatio-temporal expression of porcine CDK5 and CDK5R1 (p35) genes. Animal Biotechnology, 20(3): 133-143. 2009.

    8. Long, H., Yao, J., Tu, J. Cytological Study on Anther Development in Three Types of Brassica napus L. Male Sterility Line. Journal of Huazhong Agricultural University (Natural Science Edition), 24(6):570-575. 2005. In Chinese.

    9.Chen, M., Yang, H., Long, H., Zhang, Y., Chen, X., Yang, Z., Lei, T. Molecular characterization and transcriptional analysis of fad24 in pigs. Gene, 503(2): 208-214. 2012.

    10. Chen, Z., Gao, X., Lei, T., Chen, X., Zhou, L., Yu, A., Lei, P., Zhang, R., Long, H., Yang, Z. Molecular characterization, expression and chromosomal localization of porcine PNPLA3 and PNPLA4. Biotechnol Lett, 33(7):1327-1337. 2011.

    11. Yin, C., Long, Q., Lei, T., Chen, X., Long, H., Feng, B., Peng, Y., Wu,Y., Yang, Z. Lipid accumulation mediated by adiponectin in C2C12 myogenesis. BMB Rep., 42(10):667-72. 2009.

    12. Zhang, J., Lei, T., Chen, X., Peng, Y., Long, H., Zhou, L., Huang, J., Chen, Z., Long, Q., Yang, Z. Resistin Up-Regulates COX-2 Expression via TAK1-IKK-NF-kappaB Signaling Pathway. Inflammation, 33(1):25-33. 2009.

    13. Qi, Y., Lei, T., Zhou, L., Chen, X., Long, Q., Long, H., Jin, D., Gan, L., Yang, Z. Genomic organization, alternative splicing and tissues expression of porcine CREB3L4 gene. Mol Biol Rep., 36(7):1881-1888. 2009.

    14. Qi, Y., Lei, T., Zhou, L., Chen, X., Long, H., Long, Q., Zhang, R., Yang, Z., Gan L. Cloning, characterization, chromosomal mapping and tissue expression analysis of porcine CREB2 and CREB3. Folia Biol (Praha), 55(4):137-44. 2009.

    15. Chen, Z., Lei, T., Chen, X., Zhang, J., Yu, A., Long, Q., Long, H., Jin, D., Gan, L., Yang, Z. Porcine KLF gene family: Structure, mapping, and phylogenetic analysis. Genomics, 95(2):111-119. 2009.

    16. Yuan, J., Long, H., Lei, T., Chen, X., Yang, Z. Response of Fatty Acids to Adiponectin Expression in Matured Adipocytes. Journal of Huazhong Agricultural University (Natural Science Edition), 28(3):320-325. 2009. In Chinese